Herceptin (Trastuzumab)
Information (FAQ)
Frequently Asked Questions

(HI VALERIE 4-29-08 Send me your data on Hercepin asap.   Go Camp Carefree.  Brian  )
 

Welcome to my compendium website about

Herceptin (Trastuzumab): Beter known as  HER2-positive which is a Breast Cancer Treatment.

Herceptin Audio Track Explanation Video Click Here and Listen While you Surf.

Why do I have a page about this?   I have  kept a journal www.IamFightingCancer.com  of my very detailed medical journey which started with electrical shocks to the head. After a year assuming that it was Trigeminal Neuralgia one of the most painful disorders know to the medical field it was determined that I have a parotid gland tumor too deep to operate on. This is the salivary gland that is in your jaw on both sides of the face. If your body did not create saliva you can not eat. I have been there with a feeding tube for 4 months. Eventually after 33 radiations and 3 infusions of chemotherapy my tumor that  was too deep to operate on was  gone. I have added a lot since this site was originally  made

Then for about a year I had quarterly checkups  with no discovery of further cancer. Then I developed a persistent  cough for which the  GP Doctor could not find a cause. I was sent  for a CT Scan. I went to MD Anderson because they have all of my records. So now I have tumor metastasized in my lung along with increase fluid. A biopsy indicated it was the same type of cell that is treated with  Herceptin in patients with breast cancer. I also was diagnosed with lesions on my spinal cord. These are being treated with a monthly dose After some chemo treatments it was determined that I had excessive liver enzymes 10 times more than normal. The chemo was cut off so other than a monthly dose for my bone structure I am not taking anything for my cancer except the herceptin.  The last report showed the tumor slightly shrinking. Was this reduction cause by the herceptin treatment or was it caused by the  chemo that I did have recently or was it from the nutrition diet change or ingredients in Immuno Power. The only pill I was taking was Zoloft  for depression as my only medical pill so I was taken off that since the reduction of the chemo did not show a benefit in my liver problem. I went off the Zoloft cold turkey. My liver enzymes went down. The oncologist as assured it was due to the fact that the Zoloft was eliminated.

So I want to learn more about the Herceptin. This compendium  site will give a lot of information about Herceptin. I hope you learn something from this site. If that occurs please let me know.

Brian Nelson 713-467-3025 Click: E-mail me

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 Brian Nelson. Owner   31 Gessner Rd. ,  Houston, TX 77024   713-467-3025  Fax 713-467-3192  Click: E-mail meImportant words found on this political website. Herceptin, Trastuzumab, Her2 Positive, Breast Cancer Treatment, Fighting,
Misspelled words used to find this page 1 of 5.The important words found on this site include:
 You can find this site again by typing in the Google search engine  the very unique word " 1nitpecreH  "  which is  " Herceptin1 " backwards.      Article Word Count __________ MSW  _____   1 YouTube.com   2 Alt Tags , 3 MSW  4 Metas/Title, Keywords  Description 5 BB4/FormLetter  6 BB3/NIDAS,   7 BB1 & BB2  Follow Ups in NI.  8 URLChannelAdSense All Urls Completed. Delete 25. Old Low Ones
Herceptin® (Trastuzumab) is the only FDA-approved therapeutic for HER2 protein overexpressing metastatic breast cancer. Herceptin is a therapy for women with metastatic breast cancer whose tumors have too much HER2 protein. For patients with this disease, Herceptin is approved for first-line use in combination with paclitaxel, and as a single agent for those who have received one or more chemotherapy regimens.

Herceptin is not chemotherapy. It is a monoclonal antibody (sometimes called biologic therapy).
  • Antibodies are part of the body's normal defense against bacteria, viruses, and abnormal cells such as cancer cells.
  • Monoclonal antibodies are mass-produced in a laboratory. Their name comes from the fact that they are identical and produced from a single cell (clones).

Therapy with monoclonal antibodies is generally a more targeted form of therapy than chemotherapy.
 
Important Safety Information

Herceptin treatment can result in reduced heart function and congestive heart failure. The risk of these heart problems was higher in people who received both Herceptin and a certain type of chemotherapy (anthracycline). Your doctor may need to stop or strongly consider stopping Herceptin if you have a significant drop in your heart function.

Patients receiving Herceptin should be evaluated before and frequently monitored throughout treatment for any drop in heart function. Patients with pre-existing heart problems should be monitored more frequently. Monitoring will not identify all patients who will develop heart problems.

Serious infusion reactions and lung problems have also been seen; rarely these have been fatal. Treatment may be stopped if you begin to have a severe allergic reaction, swelling, lung problems, inflammation of the lung, or severe shortness of breath.

The worsening of low white blood cell counts associated with chemotherapy has also occurred. The most common side effects associated with Herceptin were fever, nausea, vomiting, infusion reactions, diarrhea, infections, increased cough, headache, fatigue, shortness of breath, rash, low white and red blood cells, and muscle pain.

Because everyone is different, it is not possible to predict what side effects any one person will have. If you have questions or concerns about side effects, talk to your doctor.
7 New type of chemotherapy drug approves for breast cancer

Today's topics include: Trastuzumab improves outcome in women with aggressive breast cancer, New type of chemotherapy drug approves for breast cancer treatment, Breast MRI detects more Ductal carcinoma in situ

Adding Trastuzumab commmercially called  Herceptin to chemotherapy appears to completeley eradicate tumors better than chemotherapy alon in women with HER2 positive inflammatory breast cancer. HER2 is a protein receptor that is present in certain in breast cancer. The researchers found a complete disappearance of the tumor was found in 55 percent of the women women who received trastuzumab and chemotherapy compared to 19% of women with inflammatory HER2 positive breast cancer who did not receive trastuzmab. Trastuzumab or herceptin is a member of a new category of drugs called targeted therapy agents. The food and drug association (FDA) recently approved a new chemotherapy agent  Ixabepilone  that does  does not respond to standard chemotherapy agents. Ixabepilone is the first of tne nex classification of chemotherapy agents called epothilone.  Ixabepilone is given every three weeks as a singe agent or in combinatioin with another chemotherapy drug called capecitabine.

 

One a of the main side effects of the drugs is reversible peripheral nerve damage. Other side effects include a drop in blood count, muscles and joints pain, diarrhea and fatique. Ixabepilone is marketed commercially by Bristol-Myers Squib as lexmpra.

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